详细内容（前10条）

1. ⭐ GSE300146 幕上室管膜瘤肿瘤细胞异质性的单细胞多维分析 [空间转录组学]

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、single-cell、spatial、spatial transcriptomics、transcriptomics
• 📝 描述：Contributors : Daeun Jeong ; Sara G Danielli ; Kendra Maaß ; David R Ghasemi ; Svenja K Tetzlaff ; Ekin Reyhan ; Carlos Alberto Oliveira de Biagi Junior ; Costanza Lo Cascio ; Sina Neyazi ; Andrezza Nascimento ; Rebecca Haase ; Bernhard Englinger ; Li Jiang ; Alicia-Christina Baumgartner ; Sophia Castellani ; Cuong M Nguyen ; Jacob S Rozowsky ; Olivia A Hack ; McKenzie L Shaw ; Stefan M Pfister ; Marcel Kool ; Tomasz Nowakowski ; Johannes Gojo ; Lissa Baird ; Sanda Alexandrescu ; Kristian W Pajtler ; Varun Venkataramani ; Mariella G FilbinSeries Type : OtherOrganism : Homo sapiensSupratentorial ependymomas (ST-EPNs) are aggressive and treatment-resistant pediatric brain tumors that form along the human cortex, with suspected origin from radial glia cells. Although histologically similar, ST-EPNs are molecularly classified into six distinct subgroups, many of them remaining understudied. Here, we integrated molecular cell states and spatial architecture to resolve the cellular origins and aberrant differentiation trajectories of ST-EPNs at single-cell resolution. We show that, while all ST-EPNs display a unified origin from neuroepithelial cells, different subgroups harbor highly diverse cell states and differentiation potential associated with neural or ependymal differentiation. Spatial mapping uncovered a higher-order structural tumor organization driven by presence of the mesenchymal state, and refines classical histological features based on detailed molecular resolution. By benchmarking a morpho-molecular cell-state classification system in different disease models and human tumors, we identified four cellular subtypes defined by the architecture of neurite-like extensions that mediate either self-renewal or fast, saltatory invasive phenotypes reminiscent of neurons during neurodevelopment. Collectively, our study provides a comprehensive framework for the study of ST-EPN cellular states, and reveals biologically relevant tumor compartmentalization with potential clinical implication.
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2. ⭐ GSE312984 供体内跨组织T细胞克隆扩增和肠-肝-血轴组织适应的系统映射

• ✍️ 作者：未知作者
• 🏷️ 关键词：T cell、gut、regex:gut(-?microbiome)?
• 📝 描述：Contributors : Ran Ran ; Merve Uslu ; Mohda F Siddiqui ; Douglas K Brubaker ; Martin TrapecarSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensSingle-cell RNA sequencing with paired TCR sequencing was performed on CD3+ T cells isolated from matched colon epithelium, colon lamina propria, liver, and peripheral blood samples from three healthy human donors. This study reveals tissue-specific T cell transcriptional programs and cross-tissue clonal relationships, demonstrating that expanded clones adapt their gene expression to local tissue environments while maintaining core identity markers.
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3. ⭐ GSE300646 通过生物动力学成像和 RNA 测序分析探索前列腺癌的肿瘤动力学和对基于 IL-27 的联合治疗的反应

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、sequencing
• 📝 描述：Contributors : Shreya Kumar ; Dawith Lim ; Harish Kothandaraman ; Nadia A Lanman ; David D Nolte ; John J Turek ; Marxa L FigueiredoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe use Biodynamic imaging and transcriptomics to study the response of cells to various drugs applied ex-vivo to measure and correlate the intracellular motion as a biomarker of tumor samples therapies. Prostate Cancer has been used as a model in this study. The control and IL-27 treated tumors were exposed to chemo/immunotherapy drugs ex vivo and BDI was used to profile changes in the TME. The integration of these techniques will enable informed decision-making regarding combination treatment strategies for PCa.
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4. ⭐ GSE290762 鼠伤寒沙门氏菌靶向远端结肠细胞以引发感染 [空间转录组学]

• ✍️ 作者：未知作者
• 🏷️ 关键词：spatial、spatial transcriptomics、transcriptomics
• 📝 描述：Contributors : Shanshan Li ; Ruifen Zhang ; Dan Xu ; Kai YeSeries Type : OtherOrganism : Mus musculusTo quantify the extent of Salmonella infection in different large intestine segments, we performed spatial transcriptomics to analyse which clusters of cell populations were most infected by Salmonella and determined susceptibility in the distal colonocyte of mice. To further identify that Salmonella infection-associated genes and pathways were were both significantly expressed in distal intestinal segments following Salmonella infection, we used spatial transcriptomics data to delineate the different spots on a cell-by-cell basis for subsequent cellular annotation. Our analyses reveal the susceptibility of DCC upon Salmonella infestation.
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5. ⭐ GSE281643 肠道因子 intelectin-1 通过肠-骨-肺轴维持抗哮喘环境

• ✍️ 作者：未知作者
• 🏷️ 关键词：gut、regex:gut(-?microbiome)?、regex:intestin(e|al)
• 📝 描述：Contributors : Shiyue He ; Xinyue HuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe development of extra-intestinal diseases is often accompanied by disruptions in intestinal microbiota and their metabolites. Improvement of the intestinal microenvironment frequently results in amelioration of these diseases, highlighting the need to identify key regulatory intestinal factors. In our asthma study, we identified intelectin-1 (ITLN1), predominantly expressed in the intestine, as a critical factor in maintaining intestinal bacterial homeostasis to mitigate allergic asthma via gut-bone-lung axis. We observed that reduced serum ITLN1 levels in asthmatic patients were significantly associated with increased disease severity and airway inflammation. In house dust mite (HDM)-induced asthma mouse model, ITLN1 deficiency exacerbated allergic inflammation by disrupting gut microbial homeostasis, resulting in decreased production of the beneficial short-chain fatty acid butyrate due to reduced Erysipelotrichaceae, Muribaculaceae, and Bifidobacteriaceae levels. Butyrate reduction increased CCL8 secretion by lung macrophages, which facilitated the recruitment of CD4+ T cells from the bone marrow to the lungs through the CCL8-CCR3 axis and enhanced group 2 innate lymphoid cells immune response, thereby amplifying type 2 inflammation. Elevated CCL8 levels were detected in both asthmatic patients and ITLN1-deficient asthmatic mice. Notably, supplementation with either ITLN1 or butyrate, as well as neutralization of CCL8, effectively attenuated lung allergic inflammation and improved asthma outcomes. Our findings establish ITLN1 as a crucial mediator that links gut microbial metabolism to pulmonary immune regulation, providing insights into the gut-bone-lung axis as a regulatory mechanism in asthma pathogenesis. These results position ITLN1 as a promising therapeutic target for modulating the intestinal microenvironment and mitigating systemic inflammatory responses in asthma and related disorders.
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6. ⭐ GSE246298 扩张型心肌病中的心肌纤维化：转录组学见解、组织学相关性和类器官模型验证 [RNA-seq II]

• ✍️ 作者：未知作者
• 🏷️ 关键词：cardiac、RNA-seq、transcriptomics
• 📝 描述：Contributors : Reo Hata ; Yoshinori YoshidaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensDilated cardiomyopathy (DCM) represents a leading cause of heart failure among younger adults. Despite endomyocardial biopsy (EMB) transcriptome enriching our understanding of DCM, the link between its gene expression and phenotype remains unclear. RNA-seq analysis of 58 DCM samples and 12 publicly available control samples unveiled about 25,000 transcripts. A principal component analysis highlighted a distinct DCM-control separation. WGCNA revealed four transcriptome modules strongly associated with DCM. The purple module, which is the DCM-related module, was enriched with fibrosis-related genes and showed FSTL3 as a pivotal DCM-associated gene. , We further validated using cardiac fibrosis organoid models. Concurrently, FSTL3 expression reflected cardiac organoid fibrosis intensity. Furthermore, FGFR1 expression, along with its phosphorylation in DCM myocardial tissue, was correlated with fibrosis severity. Cardiac fibrosis organoid models treated with AZD4547, a selective FGFR1 inhibitor, suppressed fibrosis-related markers, underscoring its potential therapeutic efficacy against DCM-related cardiac fibrosis.
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7. ⭐ GSE245825 扩张型心肌病中的心肌纤维化：转录组学见解、组织学相关性和类器官模型验证 [RNA-seq I]

• ✍️ 作者：未知作者
• 🏷️ 关键词：cardiac、RNA-seq、transcriptomics
• 📝 描述：Contributors : Reo Hata ; Yoshinori YoshidaSeries Type : Expression profiling by high throughput sequencing ; Third-party reanalysisOrganism : Homo sapiensDilated cardiomyopathy (DCM) represents a leading cause of heart failure among younger adults. Despite endomyocardial biopsy (EMB) transcriptome enriching our understanding of DCM, the link between its gene expression and phenotype remains unclear. RNA-seq analysis of 58 DCM samples and 12 publicly available control samples unveiled about 25,000 transcripts. A principal component analysis highlighted a distinct DCM-control separation. WGCNA revealed four transcriptome modules strongly associated with DCM. The purple module, which is the DCM-related module, was enriched with fibrosis-related genes and showed FSTL3 as a pivotal DCM-associated gene.
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8. ⭐ GSE300150 幕上室管膜瘤肿瘤细胞异质性的单细胞多维分析 [scRNA-Seq]

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、single-cell、scRNA
• 📝 描述：Contributors : Daeun Jeong ; Sara G Danielli ; Kendra Maaß ; David R Ghasemi ; Svenja K Tetzlaff ; Ekin Reyhan ; Carlos Alberto Oliveira de Biagi Junior ; Costanza Lo Cascio ; Sina Neyazi ; Andrezza Nascimento ; Rebecca Haase ; Bernhard Englinger ; Li Jiang ; Alicia-Christina Baumgartner ; Sophia Castellani ; Cuong M Nguyen ; Jacob S Rozowsky ; Olivia A Hack ; McKenzie L Shaw ; Stefan M Pfister ; Marcel Kool ; Tomasz Nowakowski ; Johannes Gojo ; Lissa Baird ; Sanda Alexandrescu ; Kristian W Pajtler ; Varun Venkataramani ; Mariella G FilbinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Rattus norvegicusSupratentorial ependymomas (ST-EPNs) are aggressive and treatment-resistant pediatric brain tumors that form along the human cortex, with suspected origin from radial glia cells. Although histologically similar, ST-EPNs are molecularly classified into six distinct subgroups, many of them remaining understudied. Here, we integrated molecular cell states and spatial architecture to resolve the cellular origins and aberrant differentiation trajectories of ST-EPNs at single-cell resolution. We show that, while all ST-EPNs display a unified origin from neuroepithelial cells, different subgroups harbor highly diverse cell states and differentiation potential associated with neural or ependymal differentiation. Spatial mapping uncovered a higher-order structural tumor organization driven by presence of the mesenchymal state, and refines classical histological features based on detailed molecular resolution. By benchmarking a morpho-molecular cell-state classification system in different disease models and human tumors, we identified four cellular subtypes defined by the architecture of neurite-like extensions that mediate either self-renewal or fast, saltatory invasive phenotypes reminiscent of neurons during neurodevelopment. Collectively, our study provides a comprehensive framework for the study of ST-EPN cellular states, and reveals biologically relevant tumor compartmentalization with potential clinical implication.
• 🔗 查看原文

9. ⭐ GSE284988 造血干细胞表观遗传谱分析鉴定出 KDR 和 PU.1 是衰老转录组和热量限制反应的调控因子

• ✍️ 作者：未知作者
• 🏷️ 关键词：aging、transcriptome、epigenetic
• 📝 描述：Contributors : Le Zong ; Bongsoo Park ; Ferda Tekin-Turhan ; Wakako Kuribayashi ; Mayuri Tanaka-yano ; Keefer Li ; Isabel BeermanSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Mus musculusThe ability to cope with fluctuations in energy supply is essential for an organism’s survival and health. While caloric restriction (CR) provides benefits towards many aspects of aging, it is associated with loss of immune function. The mechanisms by which the hematopoietic stem cells (HSCs) respond to this stress and potentially contribute to this loss of immunity remain unclear. In this study, using both lifelong and short-term CR mice models, we found that reduced energy supply leads to a decrease in total peripheral blood white blood cell production that is myeloid- and thrombo-erythroid-biased. This strategy prioritizes the production of cell types essential for survival, such as red blood cells, platelets, and innate immune cells, at the expense of adaptive immune cell differentiation. Consistent with change in blood composition, HSCs under CR are driven into cell cycle to support the myeloid differentiation rather than self-renewal. Interestingly, despite the altered hematopoietic output, lifelong CR mitigates age-associated transcriptome changes of the HSCs, but these modifications are swiftly lost after ad libitum feeding. Epigenetic profiling identified KDR as a key regulator of the CR response and experimental knockdown of Kdr in aged HSCs reproduced the more youthful aging transcriptome observed in lifelong CR HSCs. Additionally, we show that PU.1 acts as an intracellular regulator of the CR response, regulating HSC self-renewal and differentiation under CR conditions by increased binding to its target genes.
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10. ⭐ GSE283734 显示了植入 Ifnγr1WT (Cre 阴性) 和 Ifnγr1iProx1 (Cre 阳性) 小鼠体内的 B16-OVA-VEGFC 肿瘤相关淋巴内皮细胞 (LEC) 的单细胞 RNA。

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、regex:lymph(o|atic)?、scRNA
• 📝 描述：Contributors : Karakousi Triantafyllia ; Cristaldi Vanessa ; Amanda LundSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn order to determine transcriptional differences between lymphatic endothelial cell (LEC; CD45-CD31+pg38+) from B16-OVA-VEGFC melanoma tumors from Ifnγr1WT (Cre minus) and Ifnγr1iProx1 (Cre plus) mice, we sorted endothelial cells (DAPI-, CD31+, CD45-) from Ifnγr1WT (Cre minus) and Ifnγr1iProx1 (Cre plus) mice separately.
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详细内容（全部4条）

1. 利用单细胞RNA测序进行泛癌基因集发现，以实现基于深度学习的下游任务的最佳优化

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、scRNA
• 📝 描述：RNA sequencing combined with single cell analysis improves gene set selection for machine learning tasks in cancer prediction…
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2. 单细胞RNA测序揭示乳腺癌多样性

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、RNA-seq
• 📝 描述：RNA sequencing highlights diverse malignant cell states in breast cancer and identifies TCP1 as a potential target for limiting aggressive tumor behavior…
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3. 血液RNA测序显示COPD表型领域存在重叠的基因表达

• ✍️ 作者：未知作者
• 🏷️ 关键词：sequencing
• 📝 描述：RNA sequencing reveals how tumor stem cells reprogram neutrophils through prostaglandin signaling, creating a protective niche that limits immunotherapy effectiveness…
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4. 简单的补充剂混合物在治疗脑癌方面显示出显著效果。

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer
• 📝 描述：New research is challenging one of medicine’s oldest assumptions: that cancer must be attacked to be cured. By treating glioblastoma patients with a simple combination of resveratrol and copper, the researchers found dramatic reductions in tumor aggressiveness, cancer biomarkers, immune checkpoints, and stem-cell–related markers—all without side effects. Their approach focuses on “healing” tumors by eliminating harmful cell-free chromatin particles released from dying cancer cells, which normally inflame and worsen the disease. The findings hint at a future where inexpensive nutraceuticals could transform cancer therapy.
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• GSE254996 ACSS2 上调增强神经元对衰老和神经退行性疾病的抵抗力 [RNA-seq]
• GSE284229 全氟和多氟烷基物质 (PFAS) 抑制巨噬细胞的替代活化，从而破坏肝脏脂质代谢 [RNA-seq II]
• GSE284228 全氟和多氟烷基物质 (PFAS) 抑制巨噬细胞的替代活化，从而破坏肝脏脂质代谢 [RNA-seq I]
• GSE313022 STING–IFN–CH25H 脂质轴将先天免疫激活与 tau 病理联系起来 [RNA-seq]
• GSE313021 STING–IFN–CH25H 脂质轴将先天免疫激活与 tau 病理联系起来 [scRNA-seq]
• GSE306470 CUEDC1 通过 CUEDC1/CACNG4/PI3K 轴促进糖酵解代谢重编程，从而促进 ER 阳性乳腺癌的生长
• GSE303686 活化蛋白C通过释放肿瘤细胞外囊泡和转移microRNA-200a促进人肺癌进展
• GSE301964 健康志愿者暴露于模拟微重力三周后的T细胞转录组变化
• GSE294244 有前景的 miRNA，Let-7b-5p 和 miR-24-3p，具有作为靶向胰腺癌干细胞的治疗药物的潜力。[RNA-Seq]
• GSE291181 3D培养结肠癌细胞系（HCT116、SW620、DLD1）和HCEC-1CT的转录组
• GSE279909 OSA诱导的小鼠胰腺损伤模型中外泌体来源的miRNA的测序和生物信息学分析
• GSE270377 DNA甲基化和转录组整合分析揭示了与A型主动脉夹层发病机制相关的潜在标志物[miRNA-seq]
• GSE269847 DNA甲基化和转录组整合分析揭示了与A型主动脉夹层发病机制相关的潜在标志物
• GSE260717 人类β细胞上具有HLA免疫呈递功能的新型开放阅读框的蛋白质基因组学发现
• GSE246299 扩张型心肌病中的心肌纤维化：转录组学见解、组织学相关性和类器官模型验证
• GSE313083 Beckwith-Wiedemann 综合征和大后代综合征涉及甲基化组、转录组和染色质构型的改变 [Hi-C]
• GSE312980：利用 STEMdiff™ 肾脏类器官试剂盒，对 SCTi004-A hiPSC 系在 2D 或 3D 培养条件下获得的肾脏类器官进行单细胞 RNA 测序分析
• GSE283731 IFNγ依赖性代谢重编程抑制黑色素瘤中不成熟的、促转移的淋巴状态
• GSE260452 幕上室管膜瘤肿瘤细胞异质性的单细胞多维分析
• GSE254820 ACSS2 上调增强神经元对衰老和神经退行性疾病的抵抗力 [Cut&Run]
• GSE312096 抑制内皮细胞中的PAK2可通过CXCL10抑制肿瘤血管生成并促进免疫敏化
• GSE311440 脂质氧自由基防御通路及其表观遗传调控的鉴定
• GSE311353 解码神经肌肉接头重塑过程中肌肉驻留雪旺细胞的动态变化 [scRNA-seq]
• GSE309752 ATP6V0D2 通过促进 PHLPP2 溶酶体降解驱动三阴性乳腺癌进展并抑制顺铂敏感性
• GSE309454 生态历史塑造静止期酿酒酵母的转录组变异
• GSE306717 尼克酰胺通过调节 DNA 修复和细胞周期通路与舒尼替尼协同作用治疗肾细胞癌
• GSE304457 双相情感障碍和精神分裂症风险基因AKAP11编码一种自噬受体，该受体将PKA激酶网络稳态的调节与突触传递相偶联。
• GSE302268 利用间质液提取物 (IFE) 在体外模拟老年癌症。
• GSE299165 结节性硬化症相关血管平滑肌脂肪瘤的微环境分析：来自空间基因表达分析的启示
• GSE297560 太空辐射诱导不同的衰老表型：对太空旅行的启示 [批量 RNA-Seq]
• GSE297559 太空辐射诱导不同的衰老表型：对太空旅行的启示 [scRNA-Seq]
• GSE296663 小麦条锈菌IPO323的3D基因组结构
• 对 MRL/lpr 狼疮易感小鼠和 C57BL/6 对照组小鼠肾脏组织进行 GSE296302 miRNA 测序分析
• GSE296205 对 MRL/lpr 狼疮易感小鼠和 C57BL/6 对照小鼠的肾脏组织进行 RNA 测序分析
• GSE294840 硝替啶氯化物(NCD)对三阴性乳腺癌细胞的基因表达谱分析
• GSE294243 有前景的 miRNA，Let-7b-5p 和 miR-24-3p，有潜力作为靶向胰腺癌干细胞的治疗药物。
• GSE292103 果蝇物种中双性表达神经元的高分辨率单细胞转录组比较
• GSE290877 Sp100A 亚型诱导组蛋白伴侣 HIRA 定位至 PML 核体
• GSE290763 鼠伤寒沙门氏菌靶向远端结肠细胞以引发感染 [RNA-seq]
• GSE290333 对初诊和未接受药物治疗的散发性帕金森病患者外周血单核细胞进行全转录组分析
• GSE290286 RNA-seq 分析：生物活性胶束 PPP8 疗法对血红素刺激的小鼠神经元的影响
• GSE289122 FKBP9 增强 IGF2BP1 介导的 m6A 识别并促进肝细胞癌进展
• GSE288404 Olfr2 通过促进单核细胞募集驱动腹主动脉瘤的形成
• GSE287697 克拉扎珠单抗治疗对慢性抗体介导排斥反应中外周血和肾脏转录组的影响
• GSE285203 对来自 Fuchs 内皮角膜营养不良患者的人类角膜内皮细胞系进行转录组分析
• GSE285190 基于转录组的甲状腺眼病分子分型方案
• GSE284669 通过靶向抑制FSP1和GCS诱导的铁死亡来治疗肝癌和胆管癌
• GSE280635 小鼠肠固有层中 TSLP 产生细胞的单细胞水平基因表达谱。
• GSE280114 甲状腺眼病患者眼眶成纤维细胞和外周血单核细胞 (PBMC) 的批量 RNA 测序数据
• GSE278595 高强度脉冲磁场通过影响葡萄糖代谢促进大肠杆菌分裂
• GSE278434 利用超灵敏的 Pandora 测序结合机器学习筛选非侵入性 rsRNA 生物标志物以评估胚胎质量
• GSE244148 泊马度胺作为HIV感染者样本中的免疫增强剂
• GSE225567 叶酸缺乏症C57BL/6小鼠胚胎干细胞的H3K4me3 ChIP-seq
• GSE313090 慢性阻塞性肺疾病（COPD）患者肺组织的单核和空间转录组分析
• GSE313006 慢性阻塞性肺疾病 (COPD) 人类肺组织的空间转录组分析 [Xenium]
• GSE312624 长颈鹿物种形成和演化过程中的环境表观遗传变异
• GSE307391 K14-rtTA;TRE-FLBmi-1 + 4-硝基喹啉 1-氧化物 (4-NQO) 25 周 (KrTB-N (25w))、KrTB+强力霉素+4-NQO 4 周 (KrTB-DN (4w)) 和 KrTB+强力霉素+4-NQO 10 周 (KrTB-DN (10w)) 的全基因组舌上皮转录组谱。
• GSE303459 野生型小鼠耳部幼稚内皮细胞 (EC) 的 scRNA。
• GSE286902 Rroid2 在体内感染期间调节效应和记忆 CD8+ T 细胞反应
• GSE313097 通过整合网络药理学分析和实验验证，研究苏木提取物抗结直肠癌的抗癌机制
• GSE289603：Olig2对星形胶质细胞向神经元转化抑制作用的单细胞RNA测序分析
• GSE227770 水稻染色质蛋白 OsHMGB1 是一种转录促进因子，可调节磷酸盐稳态和植物生长 [ChIP-seq]
• GSE227769 水稻染色质蛋白 OsHMGB1 是一种转录促进因子，可调节磷酸盐稳态和植物生长 [ATAC-seq]
• GSE227768 水稻染色质蛋白 OsHMGB1 是一种转录促进因子，可调节磷酸盐稳态和植物生长 [RNA-seq II]
• GSE227767 水稻染色质蛋白 OsHMGB1 是一种转录促进因子，可调节磷酸盐稳态和植物生长 [RNA-seq i]
• GSE313092 M1 和 M2 髓系细胞在经典免疫类型背景下的行为不同
• GSE313081 募集的和驻留的肿瘤相关巨噬细胞对肿瘤控制的二分性
• GSE312767 放线菌属 SE50/110 在阿卡波糖发酵全过程中的转录组时间序列数据
• GSE312695 非透明细胞肾细胞癌和透明细胞肾细胞癌的基因表达分析
• GSE312644 单细胞转录组学分析S100a4基因敲除对银屑病的影响
• GSE312642 神经元来源的α-突触核蛋白对少突胶质细胞的影响 [scRNA-Seq]
• GSE312641 神经元来源的α-突触核蛋白对少突胶质细胞的影响 [RNA-Seq]
• GSE312405 空间可控唾液酸聚合物分子模式用于选择性Siglecs调节和细胞因子风暴消除
• GSE310493 正常饮食（ND）小鼠和高脂饮食（HFD）小鼠垂体组织的单细胞分析结果
• GSE306796 人类皮下 ABD/GLU/Thi 脂肪组织 RNA 测序 - 纽约市样本
• GSE297457 胆碱能神经元昼夜节律钟在RNA代谢和介导神经退行性变中的作用
• GSE295943 精确切割的肝切片的单细胞和单核转录组学
• GSE294868 EGFR 缺失可阻止肥胖相关代谢和体液应激对原代 VSMC 的早期协同作用——应激协同作用，性别依赖性
• GSE291307 肠道适应性改变可增加囊性纤维化小鼠模型中肠道基底外侧葡萄糖的摄取和糖酵解
• GSE284011 PHLPP1 Cut&Tag 分析未处理 (UT) 和 IL-4 处理的肺泡巨噬细胞
• GSE278412 结肠癌低转移克隆在逃逸晚期凋亡后
• GSE278411 VGLL1 KO 在结肠癌细胞原代培养克隆 E3、克隆 22 中
• GSE271984 微创呼吸道标本中儿童囊性纤维化气道的单细胞转录组图谱
• GSE271555 时空多组学分析揭示了恐惧记忆巩固过程中海马-杏仁核回路中独特的表观遗传和转录特征
• GSE270970 STAT3 的一种高活性剪接变体促进小鼠结肠炎症相关肿瘤的发生
• GSE267937 人类大脑中与帕金森病相关的DNA甲基化和DNA羟甲基化之间的变化
• GSE267906 用趋化因子 CCL25 处理的骨关节炎供体的人间充质干细胞的表达数据
• GSE236692 结肠癌 CC14 原代培养克隆 E3 中 ATP11C 敲低
• GSE236691 结肠癌 CC14 原代培养克隆 E3 中 CSAG1 基因敲除
• GSE236690 分析结肠癌 CC36 原代培养物中不同克隆转移潜能增加的基因表达模式
• GSE236688 分析结肠癌 CC14 原代培养物中不同克隆转移潜能增加的基因表达模式