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1. ⭐ GSA - 组学测序原始数据库【国家生物信息中心】

• ✍️ 作者：生信菜鸟团
• 🏷️ 关键词：测序、生物信息、生信
• 📝 描述：组学原始数据归档库（Genome Sequence Archive, GSA）是面向组学领域的原始数据采集、存
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2. 10x单细胞分析第一步：Cell Ranger下载+配置

• ✍️ 作者：单细胞天地
• 🏷️ 关键词：单细胞、10x
• 📝 描述：cellranger软件简介 wget下载安装cellranger 添加环境路径
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3. 详解：自身免疫性疾病中免疫细胞的代谢调控

• ✍️ 作者：小李代谢
• 🏷️ 关键词：免疫、代谢
• 📝 描述：自身免疫性疾病中免疫细胞的代谢调控是一个复杂而精细的过程，涉及多种免疫细胞类型、代谢途径和调控分子。
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4. 脚本更新–高精度空间转录组cell_niches

• ✍️ 作者：单细胞空间交响乐
• 🏷️ 关键词：空间转录组、转录组
• 📝 描述：脚本更新–高精度空间转录组cell niches
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5. 综述 | Brief.Bioinform. | 生物信息学中的分布外学习：进展与挑战

• ✍️ 作者：BioJournal Link
• 🏷️ 关键词：生物信息、生信
• 🔗 查看原文

6. Cell首发：单细胞 × CRISPR = Perturb-seq，机制研究神器！

• ✍️ 作者：生信小博士
• 🏷️ 关键词：单细胞
• 🔗 查看原文

7. Nature重磅发现：流感和新冠病毒会让休眠中癌细胞苏醒，促进癌症的复发、转移和死亡

• ✍️ 作者：食管癌前沿
• 🏷️ 关键词：癌症
• 🔗 查看原文

8. 食管鳞癌新辅助免疫加化疗两周期与三周期的疗效和安全性比较

• ✍️ 作者：食管癌前沿
• 🏷️ 关键词：免疫
• 🔗 查看原文

9. metasens 包用于 meta分析中的敏感性分析:LFK 不对称性指数检验和Doi 图

• ✍️ 作者：R 学习践行者
• 🏷️ 关键词：TME
• 📝 描述：LFK 不对称性指数检验 和 Doi 图（Doi Plot） 是一组 新型的偏倚检测工具，近年来在 Meta 分析方法学中逐渐取代或补充传统的 漏斗图（funnel plot） 与 Egger’s test。
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10. python单细胞学习：（IF=48.8）顶刊杂志复现（一）

• ✍️ 作者：生信技能树
• 🏷️ 关键词：单细胞
• 📝 描述：新的一篇python单细胞开始学习了，来！
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1. ⭐ GSE305686 单细胞转录组学揭示牛肌内脂肪和皮下脂肪中脂肪祖细胞的发育阶段和数量存在显著差异

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、carcinoma、immune、immunity、TME、cardiovascular、cardiac、glioma、resistance、TCGA、DepMap、depmap、RNAseq、single.cell、single-cell、scRNA、scDNA、scATAC、spatial、Visium、genome、genomics、transcriptome、transcriptomics、proteome、Seurat、Scanpy、epigenetic、epigenome、histone、enrichment
• 📝 描述：Contributors : Zhendong Tan ; Pengcheng Lyu ; Honglin JiangSeries Type : Expression profiling by high throughput sequencingOrganism : Bos taurusBackground: Intramuscular fat (IMF), the white adipose tissue deposited between skeletal muscle fibers, is a key determinant of beef quality due to its contribution to meat, flavor, juiciness and tenderness. However, IMF develops later and grows more slowly, compared to other fat depots such as subcutaneous fat (SF) in cattle. The cellular and molecular mechanisms underlying the delayed development and slower growth of IMF compared to other fat depots remain poorly understood. Results: We performed single-cell RNA sequencing (scRNA-seq) on the stromal vascular fractions (SVFs) from IMF and SF of adult Angus crossbred steers as well as the mononuclear cell fractions (MCFs) from skeletal muscles of newborn Angus crossbred bull calves, with each tissue type collected from two animals. A total of 14,802 cells from 6 animals were sequenced. A clustering analysis revealed that these cells comprised ten cell types, including adipose progenitor cells (APCs), muscle satellite cells (MuSCs), myoblasts, smooth muscle cells, and various immune cell populations. The SF SVF from adult cattle harbored a significantly higher proportion of APCs than the IMF SVF. The MCFs from newborn calves did not contain detectable APCs. A subclustering analysis revealed that the APCs comprised six subpopulations (C0–C5), among which C3 and C5 were absent in the IMF SVF while C1 was markedly less abundant in the IMF SVF than the SF SVF. A gene set variation analysis and a pseudotime trajectory analysis showed that C1 and C3 represented more differentiated APCs, with higher expression of genes involved in adipogenesis, such as PPARG, ADAM12, and PPARGC1A, whereas subclusters C0 and C4 represented undifferentiated, uncommitted APCs, with higher expression of genes involved in DNA replication and cell adhesion, compared to the other subclusters. Conclusions: Overall, this single-cell transcriptomics study suggests two major differences in APCs between IMF and SF in adult cattle: (1) IMF contains fewer APCs than SF; (2) APCs in IMF are adipogenically less committed and differentiated compared to APCs in SF. These differences may explain why IMF develops later and grows more slowly than SF in cattle. This study also suggests that, in cattle, intramuscular fat begins to develop postnatally, challenging the widely held belief that it forms during late g…
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2. ⭐ GSE272588：具有不同克隆谱系命运、转录组和表面标志物的多能祖细胞产生两棵造血树

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、TME、cardiac、glioma、resistance、TCGA、DepMap、depmap、scRNA、scATAC、spatial、genome、genomics、transcriptome、transcriptomics、proteome、proteomics、Seurat、Scanpy、epigenetic、epigenome、histone
• 📝 描述：Contributors : Fuwei Shang ; Xi Wang ; Hans-Reimer RodewaldSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusMultipotent progenitors (MPP) are the quantitative source of native hematopoiesis that have been thought to be replenished slowly by hematopoietic stem cells (HSC). However, recent fate mapping studies have revealed two developmentally distinct populations of MPP, HSC-derived MPP (hMPP), and HSC-independent, embryonic MPP (eMPP). These data raise fundamental questions on the distinctions and functions of these progenitors. Here, we mapped the clonal dynamics of the two independent MPP systems, using in situ barcoding, and barcode linkage (hMPP), or disconnect (eMPP), with HSC. The cumulative output of eMPP to hematopoiesis was 35%, and their output was enriched for lymphoid fates. Conversely, hMPP output was enriched for myeloid-restricted fates. Distinguishing HSC from eMPP outputs revealed that only ~15% of adult HSC clones underwent multilineage differentiation (lymphoid, myeloid, and erythroid). To prospectively identify eMPP, we developed PolySMART for joint profiling of PolyloxExpress RNA barcodes, surface markers, and transcriptomes, and we found that the plasma cell marker CD138 enriches for eMPP. CD138+ MPP are primed for self-renewal and toward lymphoid fate, and become largely but not completely replaced by CD138− MPP over time, which may contribute to the loss of lymphoid output with age. Taken together, adult hematopoiesis consists of two distinct lineage trees. The source of the “eMPP tree” substantially contributes to hematopoiesis before it declines, while the HSC-hMPP tree supplies hematopoiesis life-long. Our molecular determinants distinguishing the two MPP systems may open avenues to further explore these unexpected layers of hematopoiesis.
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3. ⭐ GSE306525 利用多模态单细胞分析解析人类免疫细胞在病毒和化学物质暴露下的表观基因组动态

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、immune、TME、cardiac、glioma、DepMap、depmap、Hi-C、single.cell、single-cell、scRNA、scDNA、scATAC、spatial、genome、genomics、Seurat、Scanpy、epigenetic、epigenome、histone、clustering
• 📝 描述：Contributors : Irem B Gunduz ; Bei Wei ; Aaron J Wilk ; Madeline J Lee ; Catherine Blish ; Fabian Muller ; William J GreenleafSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensPathogen and chemical exposures lead to profound remodeling of the gene-regulatory landscape across human immune cell populations. Here, we present a single-nucleus chromatin accessibility atlas of human immune cells of individuals exposed to HIV-1, COVID-19, Influenza virus, organophosphates as well as healthy controls that provides insights into gene regulation driven by these cell-extrinsic stimuli. This atlas comprises 271,299 cells and 319,420 candidate regulatory elements that exhibited dynamic accessibility associated with gene expression across immune cell states. Our longitudinal HIV cohort revealed epigenetic signatures of T cell exhaustion, manifested in changes in the accessibility of binding sites for the FOXP family transcription factors. We further identified changes in the accessibility of candidate regulatory elements in CD14 monocytes upon SARS-CoV-2 exposure that are associated with a switch in NF-κB to AP-1-based regulation of cytokine networks. By integrating single-cell profiles of DNA methylation from matched samples we create a multimodal epigenome atlas of human immune cells across exposure states using the accessibility-derived candidate regulatory elements. Both modalities exhibit complementary epigenetic signatures at transcription factor binding sites associated with cell state, as exemplified in the process of memory formation in T-cells. Finally, by linking potentially regulatory DNA methylation signatures to changes in chromatin accessibility in monocytes, we identify AP1 motifs exhibiting epigenetic dynamics, indicating selective remodeling in TF networks in severe cases of COVID-19.
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4. ⭐ GSE305657 慢性应激破坏肝脏犬尿氨酸途径，从而抑制肝脏 CD8+ T 细胞免疫并促进肝癌发生

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、immune、immunity、TME、cardiac、glioma、kinase、resistance、DepMap、depmap、scRNA、scDNA、scATAC、spatial、spatially、genome、proteome、Seurat、Scanpy、histone、pathway
• 📝 描述：Contributor : Renhui SunSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic psychological stress is associated with liver disease mortality, yet the reasons are unclear. Here we describe a stress-responsive brain-liver regulatory circuit that impairs CD8+T cell immunity and promotes the progression of liver cancer. Specifically, psychological stress-mediated dysregulation of catecholamine/β2-adrenergic receptor (ADRB2) signaling leads to reduced number and effector functions of liver CD8+ T cells by suppressing the expression of quinolinate phosphoribosyl transferase (QPRT) in hepatocytes and shifting hepatic Kyn metabolism from de novo nicotinamide adenine dinucleotide (NAD+) synthesis to kynurenic acid (KA) production. Notably, ADRB2/QPRT expression in human hepatocytes correlates with NAD+ and KA levels, as well as CD8+T cells frequency and function in human liver tissues.
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5. ⭐ GSE243826 野生型和ATF6转基因小鼠肝脏免疫细胞的单细胞转录组学特征分析

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、immune、immunity、TME、glioma、resistance、single.cell、single-cell、scRNA、scDNA、scATAC、spatial、spatially、genome、genomics、transcriptome、transcriptomics、Seurat、Scanpy、enrichment
• 📝 描述：Contributors : Kristian Unger ; Mathias Heikenwälder ; Xin LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related mortality with limited therapies. While endoplasmic reticulum (ER)-stress and the unfolded protein response (UPR) are implicated in HCC, the involvement of the UPR-transducer activating transcription factor 6 alpha (ATF6α) remains unclear. We isolated CD45+ cells from livers of wild type and hepatocyte-specific nATF6 overexprerssion mice for scRNAseq to decrible the the immune cell population.
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6. ⭐ GSE288484 对 PTEN 蛋白缺陷型前列腺肿瘤的转录网络分析揭示了显著的基质重编程和衰老旁分泌通讯的迹象。

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、TME、cardiac、glioma、kinase、resistance、TCGA、DepMap、depmap、scRNA、scDNA、scATAC、spatial、genome、transcriptome、proteome、Seurat、epigenetic、clustering
• 📝 描述：Contributors : Ivana Rondon-Lorefice ; Jose I Lopez ; Aitziber Ugalde-Olano ; Maite Zufiaurre ; Ianire Astobiza ; Natalia Martin-Martin ; Laura Bozal-Basterra ; Saioa Garcia-Longarte ; Amaia Zabala ; Sofia Rey ; Aida Santos-Martin ; Miguel Unda ; Ana Loizaga-Iriarte ; Mariona Graupera ; Paolo Nuciforo ; Arkaitz Carracedo ; Isabel MendizabalSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAmong the extensive genomic alterations in prostate cancer, PTEN deletion stands out as one of the most consistently observed events. PTEN loss in prostate tumors is primarily associated with cancer cell proliferation and survival through the activation of the PI3K-AKT-mTOR signaling pathway. However, the use as a robust biomarker in clinical practice is hampered by its complex epigenetic, transcriptional, and post-translational regulation. In situ protein assessment by immunohistochemistry (IHC) captures PTEN protein status, but it does not report on associated tumor microenvironment remodeling. Here, we undertook an approach that combined PTEN immunoreactivity analysis with high-throughput transcriptional analysis to gain insights into the downstream functional effects of PTEN protein loss in primary tumors. Our extensive bioinformatic analyses highlighted stromal remodeling as a prominent cancer cell-extrinsic process associated with PTEN loss. By extending our transcriptomic computational strategy to Pten-loss driven murine prostate cancer, we validated the causal role of Pten in the stromal reaction observed in clinical specimens. Mechanistically, we provide experimental evidence for the activation of a paracrine program that encompasses enhanced TGF-β signaling and that is compatible with the secretome of PTEN-deficient senescent cancer cells. Finally, our findings enable the sub-stratification of tumors with PTEN loss based on their senescence-associated stroma remodeling program to distinguish indolent from aggressive cases. Our study provides relevant biological context to the cellular and molecular alterations unleashed upon PTEN protein loss in prostate cancer.
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7. ⭐ GSE281103 TGF-β驱动的Mafb通过竞争性结合WTAP减弱IGFBP2的降解修饰，诱导卵巢癌转移和免疫失调。

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、immune、immunity、TME、metabolic、cardiac、glioma、resistance、TCGA、DepMap、depmap、scRNA、scDNA、scATAC、Visium、genome、Seurat、Scanpy、epigenetic
• 📝 描述：Contributors : Qinke Li ; Qiang Yi ; Siying Zhang ; Zhu YangSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis ChIP-seq dataset examines the genome-wide binding profile of transcription factor MAFB in ovarian cancer cells to investigate its role in tumor progression and immune dysregulation. Using ID8 mouse ovarian cancer cells with MAFB overexpression, we performed chromatin immunoprecipitation followed by high-throughput sequencing to identify MAFB binding sites. Surprisingly, our analysis revealed that IGFBP2, a key mediator of MAFB-driven tumor metastasis and immune modulation, was not a direct transcriptional target of MAFB. The ChIP-seq data was generated using an anti-MAFB antibody, with IgG as control. Peak calling was performed using MACS2 (version 2.2.7.1), and peak annotation was conducted using the ChIPseeker R package. Motif analysis was performed with HOMER (v4.11.1), and differential analysis was conducted with MAnorm.
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8. ⭐ GSE306588 移植肾中核磷蛋白 1 乳酸化诱导铁死亡触发波，加剧移植肾功能延迟恢复 [RNA-Seq]

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、cardiac、kinase、resistance、TCGA、RNA-seq、RNAseq、DNA-seq、ChIP-seq、ATAC-seq、scRNA、scDNA、scATAC、spatial、genome、genomics、Seurat、Scanpy、epigenetic、histone
• 📝 描述：Contributors : Xinyuan Li ; Xin Gou ; Tianxin Lin ; Weiyang HeSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe effects of NPM1 lactylation on transcriptional profiling in HK-2 cells
• 🔗 查看原文

9. ⭐ GSE217362 颅骨来源间充质干细胞移植对实验性脊髓损伤功能恢复的影响

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、immune、immunity、TME、cardiac、glioma、DepMap、depmap、scRNA、scDNA、scATAC、spatial、spatially、genome、genomics、proteome、Scanpy、enrichment
• 📝 描述：Contributor : Kiyoharu ShimizuSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusWe compared the therapeutic effects and mechanism of transplanted rat cranial bone-derived mesenchmay stem cell (rcMSCs) and rat bone marrow-derived mesenchymal stem cell (rbMSCs) in a rat cervical spinal cord injury (cSCI) model.We performed gene expression profiling analysis using data obtained from RNA-seq of rcMSCs and rbMSCs
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10. ⭐ GSE309248 利用人诱导多能干细胞生成脊髓类器官，并使其向腰椎方向分化

• ✍️ 作者：未知作者
• 🏷️ 关键词：tumor、cancer、carcinoma、immune、TME、glioma、TCGA、single.cell、scRNA、scDNA、spatial、genome、genomics、transcriptome、proteome、Seurat、epigenome、enrichment
• 📝 描述：Contributors : Li Jun Loh ; Joel Mason ; Pratibha Panwar ; Shila Ghazanfar ; Kwaku Dad Abu-Bonsrah ; Forough Habibollahi ; Brett J Kagan ; Bradley Turner ; Samantha K BartonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensOrganoids offer a powerful platform to model human development and disease in vitro while preserving key features of in vivo tissue architecture and complexity. In this study, we developed a novel, reproducible protocol to generate human induced pluripotent stem cell (iPSC)-derived spinal cord organoids specifically patterned to the lumbar region, a segment rarely modelled in vitro. These organoids recapitulate the ventral spinal cord’s cytoarchitecture and exhibit functional neuronal activity, providing a physiologically relevant system for investigating human spinal cord development and neurodegenerative disease mechanisms. Furthermore, we applied 10x Genomics single-cell RNA sequencing to generate the first high-resolution transcriptional map of human lumbar spinal cord organoids, revealing their cellular diversity and molecular signatures.
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1. 靶向 ATM-TGS1-BRCA1 轴克服胰腺癌的遗传毒性治疗耐药性。

• ✍️ 作者：未知作者
• 🏷️ 关键词：耐药
• 📝 描述：Secret hovertext: 胰腺癌 （PAAD） 仍然是最致命的恶性肿瘤之一，主要是因为它对化疗和放疗等遗传毒性疗法具有很强的耐药性。了解这种耐药性的潜在机制对于改善临床结果至关重要。在这里，我们确定了三甲基鸟苷合酶 1 （TGS1） 以前以其在 RNA 修饰中的作用而闻名，作为同源重组 （HR） 修复的关键介质，特别有助于 PAAD 的耐药性。TGS1 在 PAAD 组织中显著过表达，与晚期疾病分期、治疗耐药和患者预后不良密切相关。DNA 损伤后，ATM 激酶在丝氨酸残基 S389 和 S531 处磷酸化 TGS1，这介导其与 BRCA1 的直接相互作用以及随后将 BRCA1 募集到 DNA 损伤位点。磷酸化依赖性相互作用提高了 HR 修复效率，使癌细胞能够在遗传毒性应激中存活下来。TGS1 的耗竭或药理学抑制诱导 HR 缺乏，并显着增强对 DNA 损伤剂的敏感性，特别是 PARP 抑制剂，在体外 PAAD 细胞系
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1. ⭐ Answer ALS 完成了完整数据集的发布，并将 ALS TDI ARC 研究数据整合到 Neuromine 中。

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、TME、cardiac、scRNA、scDNA、scATAC、spatial、genome、proteome、Seurat、epigenome
• 📝 描述：Answer ALS and ALS TDI data integration in Neuromine offers researchers RNA sequencing and multi-omics insights from over 2,500 ALS patient profiles to accelerate therapy…
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2. ⭐ KATMAP通过基因敲低数据推断剪接因子活性和调控靶点

• ✍️ 作者：未知作者
• 🏷️ 关键词：carcinoma、TME、TCGA、scRNA、scDNA、scATAC、spatial、Seurat
• 📝 描述：RNA sequencing reveals how KATMAP predicts splicing factor activity and regulatory targets, offering new insights into RNA processing and gene regulation…
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3. ⭐ Nicheformer——一种揭示细胞在组织中如何组织的新型基础模型

• ✍️ 作者：未知作者
• 🏷️ 关键词：cancer、TME、TCGA
• 📝 描述：RNA sequencing combined with spatial transcriptomics allows Nicheformer to reconstruct cellular neighborhoods, revealing how tissue structure and gene expression are…
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• 文献分享–AI驱动的空间细胞表型组学提升非小细胞肺癌风险分层效能
• 当大家扎堆做乳酸的时候，机智的我偷偷的看上了这个代谢物…….
• 如果你想从代谢角度申请国自然，推荐四个高端思路给你……

• GSE242831 野生型小鼠和 ATF6 转基因小鼠肝脏组织的基因组拷贝数特征。
• GSE217688 卡波西肉瘤相关疱疹病毒通过调节假尿苷途径增强裂解性复制
• GSE290937 多组学分析恶病质靶组织揭示了对癌症的时空协调反应
• GSE308378 最小编辑，最大效应：单氨基酸缺失的 SCID 猪延长生存期 [ChIP-seq]
• GSE295294 大鼠胎盘MATE1特异性表达导致二甲双胍和1-甲基-4-苯基吡啶在胎儿转运中的物种差异
• GSE294466 人类颈动脉斑块的 Xenium 空间转录组学
• GSE294291 人类颈动脉斑块单细胞转录组学 V2
• GSE293415 小鼠卵子发生和植入前胚胎发育过程中H2A.Z掺入的主要浪潮
• GSE244213 6月龄野生型和肝细胞特异性ATF6过表达小鼠的肝脏转录组谱
• GSE244212 3月龄野生型和肝细胞特异性ATF6过表达小鼠的肝脏转录组谱
• GSE308949 肺肉芽肿中结核分枝杆菌肽特异性T细胞的转录谱
• GSE308377 最小编辑，最大效应：单氨基酸缺失的 SCID 猪延长生存期 [RNA-Seq]
• GSE306531 移植肾中核仁磷蛋白1乳酸化诱导铁死亡触发波，加剧移植肾功能延迟恢复
• GSE281599 组织粘附性、抗菌性和抗氧化性水凝胶密封剂，用于密封结直肠吻合口漏并预防术后粘连
• GSE248865 热量限制和皮质酮治疗引起的糖皮质激素受体顺式重编程。
• GSE281186 PRMT3介导的脑肿瘤干细胞的细胞和分子调控。
• GSE292505 氡暴露延缓银屑病小鼠模型中皮肤病变的发生
• GSE276603 CFAP20 挽救了阻滞的 RNAPII，使其无法进入同向复制体路径
• 利用电荷改变型可释放转运体将GSE295750 RNA递送至角膜内皮
• GSE287187 Chameau (HBO1) 在果蝇中以温度依赖的方式调控饥饿
• GSE301362 衰老细胞清除疗法识别并逆转细胞衰老，从而揭示其作为肠道再生和功能障碍（与衰老相关）驱动因素的作用
• GSE298149 热量限制的结果是由增强的糖皮质激素节律驱动的。
• GSE248866 热量限制的结果是由增强的糖皮质激素节律驱动的。
• GSE248864 肝脏糖皮质激素受体 (GR) 驱动对热量限制的昼夜适应
• GSE285470 代谢稳态系统调节必需代谢物的聚集和毒性
• GSE288422 研究发现 KRT17 表达升高可增强铂耐药卵巢癌类器官对靶向治疗的敏感性
• GSE217588 溶质载体家族37成员3在肝细胞癌中的作用
• GSE277042：Armh4对衰老影响的转录组分析
• GSE249285 体外肺类器官模型用于异常基底样细胞的诱导和激活
• GSE281155 RNA-seq 分析了经 DEHP 处理的 Sox9-eGFP 小鼠胎儿睾丸的 RNA-seq 数据。